Nmcli

Network Manager Command Line - is used for controlling NetworkManager and reporting network status.

Check connection status of interfaces

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nmcli dev status

# nmcli dev status

DEVICE      TYPE      STATE         CONNECTION 
docker0     bridge    connected     docker0    
virbr0      bridge    connected     virbr0     
enp0s3      ethernet  connected     enp0s3     
virbr0-nic  ethernet  disconnected  --         
lo          loopback  unmanaged     --   

Turn Connection Up or Down

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nmcli connection down <interface> or nmcli connection up <interface>

# nmcli connection down ens192
Connection 'ens192' successfully deactivated (D-Bus active path: /org/freedesktop/NetworkManager/ActiveConnection/1)

# nmcli connection up ens192
Connection 'ens192' successfully activated (D-Bus active path: /org/freedesktop/NetworkManager/ActiveConnection/2)

Turn Autoconnect On/Off

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Turn on:

# nmcli connection modify ens192 connection.autoconnect yes

Turn of:

# nmcli connection modify ens192 connection.autoconnect no

Or you can do the typical way of editing:

# vi /etc/sysconfig/network-scripts/ifcfg-ens192
.
.
.
ONBOOT=<yes/no>